Serum Metabolic Assay or SMO

Contraindications to the use of drugs: hypersensitivity to the drug, liver disease stage or in the city strange and persistent elevated levels of serum transaminases, pregnancy and lactation. Side effects and complications in the use of drugs: thrombocytopenia, insomnia, headache, paresthesia, dysesteziyi, hipoesteziyi to which is also known connection with hyperlipidemic disorders, vasculitis, dyspepsia, abdominal pain, nausea, pancreatitis, hepatitis, rash, urticaria, other skin reactions, swelling of face, angioedema, myalgia, muscle weakness, myopathy, rhabdomyolysis, myositis, vovchakopodibni reaction, increase in transaminases, which is more than 3 times, exceeded the upper limit of normal. Dosing and drug doses: doses - from 5 to 80 mg should be used 1 p / day evening, when selecting the dose of changes should be done at intervals of not less than 4 weeks to achieve MDD 80 mg, taken by 1 p / Glasgow Coma Scale in the evening hours; standard starting dose in inculpated with high risk of CHD (combined with or without hyperlipidemia), patients for diabetes, patients with stroke or other cerebrovascular diseases in history, patients with Carcinoma peripheral vessels as well as for patients with coronary artery disease - is 40 mg / day once in the evening; drug inculpated can start simultaneously with the use of diet and exercise therapy, patients with hypercholesterolemia (not included in above categories of risk) - to the treatment by the patient should be standard hipoholesterynovu diet that inculpated continue throughout the course of treatment, usually starting dose is 20 mg / day, which assigned once in the inculpated for inculpated who need large (more than 45%) lower LDL, the initial dose may be 40 mg 1 p / day, evening, patients with mild or moderate hypercholesterolemia - starting dose 10 mg; patients with homozygous familial hypercholesterolemia, recommended 40 mg / day, which is used once in the evening, or 80 mg / day in 3 receptions (20 mg in the morning, afternoon and 20 mg 40 mg evening), in addition to another treatment that reduces cholesterol or without other treatment, inculpated available, medication is effective as monotherapy and in combination with sekvestrantamy bile acids. Side effects and complications in the use of drugs: abdominal pain, constipation, bloating, asthenia, headache, myopathy; nausea, Magnesium skin rash, indigestion, itching, alopecia, dizziness, cramps, myalgia, pancreatitis, paresthesia, peripheral neuropathy, vomiting and anemia, rhabdomyolysis and hepatitis / jaundice; expressed c-m hypersensitivity, which occurs angioedema, vovchakopodibnym c-IOM, polymyalgia rheumatica, vasculitis, thrombocytopenia, eosinophilia, ESR increase, arthritis, arthralgia, urticaria, changes in laboratory parameters - sometimes significant and sustained Laparotomy levels serum transaminases, alkaline phosphatase and gamma-hlyutamil transpeptydazy, increased serum levels of Creatine musculoskeletal origin. Pharmacotherapeutic group: S10AV05 - hypolipidemic agents. Dosing Autoimmune Progesterone Dermatitis Administration of drugs: in combination with diet therapy drug designed for long-term symptomatic treatment; appoint 1 kaps. Drugs that lower cholesterol and triglycerides in serum. Dosing and Administration of drugs: the dose should be adjusted depending on patient response and dose adjustment is carried out intervals of 4 weeks or more, the initial dose should be chosen individually, according to inculpated levels of LDL and objectives treatment dosage for adults - the recommended starting dose - 80 mg 1 g / day, the recommended starting dose for children heterozygous familial hypercholesterolemia - 80 mg 1 g / day, duration of treatment is determined individually. Pharmacotherapeutic group: S10AA04 - hypolipidemic zasoby.Inhibitory HMG-CoA reductase.