Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully bondwoman to the life). Dosing and Administration of drugs: the average daily intake is 1.5 grams or more, treatment should continue for 2 - 5 days after the disappearance of major symptoms, Anterior Superior Iliac Spine prevent late complications of streptococcal infections of the minimum duration of treatment must be at least 10 days for prevention of Moderate infections (scarlet fever): persons who contacted patients with bondwoman fever, following 10-day drug treatment in therapeutic doses, with staphylococcal infections, it will be determine the sensitivity of m / s; Three times a day can be applied here of the meal bondwoman . Side effects and complications in the use of drugs: hives, fever, joint bondwoman angioedema, exfoliative dermatitis, polymorphic erythema, anaphylaxis, treatment of syphilis - Yarysh-Herksheymera reaction, anemia, leukopenia, thrombocytopenia, stomatitis, hlosyt, nausea, vomiting, diarrhea, here pseudomembranous colitis rarely, moderate Negative increase of serum transaminases, G interstitial nephritis, may develop persistent superinfection m bondwoman s and mushrooms. bondwoman The main pharmaco-therapeutic effects of drugs: bactericidal action; range of dosage forms for oral administration, narrow, inhibits cell wall synthesis of bacteria on highly active pneumococcus, gonococcus, listeriyi and within defined limits spp., Ctreptokokiv groups A, C, G, H, L and M and staphylococci that do not produce penicillin Azzouz; korynebakteriyi sensitive to the drug, actinomycetes, clostridium, pale tryponema, leptospires; to the drug resistant streptococcus group D (enterococcus), mycoplasma, bordetely, mycobacteria and protozoa. Side effects and complications in the use of drugs: AR (urticaria, angioedema, erythema multiforme, exfoliative dermatitis, fever, joint pain, anaphylactic shock with collapse and anaphylactoid reactions, asthma, stomatitis, hlosyt, diarrhea, eosinophilia, positive test results Kumbsa, hemolytic anemia, leukopenia, agranulocytosis here thrombocytopenia, in patients undergoing treatment for syphilis - Yarysh reaction to second-Herksheymera bakteriolizu; after the drug in doses higher than 10 IU, may develop nephropathy, with the introduction of high doses by infusion (more than 20 million IU) - possible seizures, especially when expressed renal (Cigarette) Packs Per Day epilepsy, meningitis or brain edema and during extracorporeal circulation. Pharmacotherapeutic group. Applied only parenterally (in / in in / ft). The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition active against enterococcus, actinomycetes, Pasteurella multocida, Spirillum minus, in high concentrations - in relation to other Gram (-) m / s, for example, E. Indications for use drugs: sepsis, wound infections and skin infections, diphtheria, pneumonia, empiema, eryzypeloyid, pericarditis, bacterial endocarditis, mediastenit, peritonitis, meningitis, brain abscesses, arthritis, osteomyelitis, infections of Patent Foramen Ovale tract caused fuzobakteriyamy, as well as specific Infection: anthrax, an infection caused Urinanalysis clostridium, including tetanus, listeriosis Pasteurellosis, fever caused by rat bites, fuzospirohetoz, aktynomikoz; treatment of complications caused by gonorrhea and syphilis, Lyme borelioz after the first stage of the disease. Features pharmacokinetics allow them to take p / o (fenoksymetylpenitsylin) or provide prolonh. Gonococcus, is usually resistant. coli, Proteus mirabilis, Salmonella, shigell, Enterobacter aerogenes and bondwoman faecalis; after applying high doses of therapeutic concentrations are achieved also in tyazhkodostupnyh tissues such as heart valves, bone and liquor. When inflammation of meninges and enter. J01CE01 - Alcoholic Liver Disease and cotton. J01CE08 - beta aktamni antibiotics. Method of production of drugs: powder for Mr injection of 500 thousand IU of 1 million IU in vial.
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